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What are the symptoms of melioidosis?

– cough with normal sputum (the mixture of saliva and mucus that can rise into the throat from coughing) or no sputum, called a nonproductive cough.
– chest pain during breathing.
– high fever.
– headache and general muscle soreness.
– weight loss.

Burkholderia pseudomallei (also known as Pseudomonas pseudomallei) is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It is a soil-dwelling bacterium endemic in tropical and subtropical regions worldwide, particularly in Thailand and northern Australia.

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Moreover, How common is melioidosis?

Melioidosis is a rare disease in the United States, but it is common in tropical or subtropical areas of the world, including Southeast Asia, Africa, and Australia. The signs and symptoms of the disease can vary greatly and may mimic those of tuberculosis or common forms of pneumonia.

Secondly, What does Burkholderia pseudomallei cause?

Burkholderia pseudomallei is the causative agent of melioidosis, a serious disease affecting humans and animals. Infection with B. pseudomallei can lead to septicemia and pneumonia in susceptible individuals (Godoy et al., 2003). Melioidosis is also referred to as Whitmore disease.

Simply so, What causes melioidosis?

The disease is caused by the bacterium Burkholderia pseudomallei. It is predominately a disease of tropical climates, especially in Southeast Asia and northern Australia where it is widespread. The bacteria causing melioidosis are found in contaminated water and soil.

How do you get melioidosis?

People can get Melioidosis through direct contact with contaminated soil and surface waters. Humans and animals are believed to acquire the infection by inhalation of contaminated dust or water droplets, ingestion of contaminated water, and contact with contaminated soil, especially through skin abrasions.


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How is melioidosis diagnosed?

Melioidosis is diagnosed by isolating Burkholderia pseudomallei from blood, urine, sputum, skin lesions, or abscesses; or by detecting an antibody response to the bacteria.

Where is Burkholderia pseudomallei found?

Melioidosis is an infection caused by the bacteria, Burkholderia pseudomallei. This bacteria is not found in the United States, except for Puerto Rico, but is common in many other parts of the world including southeast Asia and northern Australia.

What are the characteristics of the disease melioidosis caused by Burkholderia pseudomallei?

pseudomallei experience no symptoms, but those who do experience symptoms have signs and symptoms that range from mild, such as fever, skin changes, pneumonia, and abscesses, to severe with inflammation of the brain, inflammation of the joints, and dangerously low blood pressure that causes death.

What is melioidosis disease?

Melioidosis, also called Whitmore’s disease, is an infectious disease that can infect humans or animals. The disease is caused by the bacterium Burkholderia pseudomallei. It is predominately a disease of tropical climates, especially in Southeast Asia and northern Australia where it is widespread.

How does melioidosis affect the body?

melioidosis can spread from the skin through the blood to become a chronic form of melioidosis affecting the heart, brain, liver, kidneys, joints, and eyes (disseminated). Symptoms of disseminated melioidosis infection include fever, weight loss, stomach or chest pain, muscle or joint pain, headache, and seizures.

What organism causes melioidosis?

The disease is caused by the bacterium Burkholderia pseudomallei. It is predominately a disease of tropical climates, especially in Southeast Asia and northern Australia where it is widespread. The bacteria causing melioidosis are found in contaminated water and soil.

Where is melioidosis found?

The disease is caused by the bacterium Burkholderia pseudomallei. It is predominately a disease of tropical climates, especially in Southeast Asia and northern Australia where it is widespread. The bacteria causing melioidosis are found in contaminated water and soil.

How is melioidosis transmitted?

People can get Melioidosis through direct contact with contaminated soil and surface waters. Humans and animals are believed to acquire the infection by inhalation of contaminated dust or water droplets, ingestion of contaminated water, and contact with contaminated soil, especially through skin abrasions.

Can melioidosis be cured?

Some patients with very mild infections can probably be cured by oral agents alone. Ceftazidime is the mainstay of acute-phase treatment, with carbapenems reserved for severe infections or treatment failures and amoxicillin/clavulanic acid (co-amoxiclav) as second-line therapy.

How does Burkholderia pseudomallei cause disease?

Melioidosis, also called Whitmore’s Disease, is an infectious disease caused by a bacterium called Burkholderia pseudomallei (previously known as Pseudomonas pseudomallei). The bacteria are found in contaminated water and soil and spread to humans and animals through direct contact with the contaminated source.

How is Burkholderia pseudomallei naturally transmitted?

B. pseudomallei bacteria are found in contaminated soil and water and spread to humans and animals through direct contact with the contaminated source.

How is melioidosis prevented?

Persons with open skin wounds and those with diabetes or chronic renal disease are at increased risk for melioidosis and should avoid contact with soil and standing water. Those who perform agricultural work should wear boots, which can prevent infection through the feet and lower legs.


Last Updated: 8 days ago – Co-authors : 10 – Users : 7

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