How do statins affect the brain?

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Some statin users have reported that they experienced memory loss while taking the medication. The U.S. Food and Drug Administration (FDA) updated its safety information for statins to include memory loss, forgetfulness, and confusion as possible risks, or side effects of taking statins.

Simvastatin and atorvastatin are the most lipophilic while pravastatin and Crestor are the least. The statins that cross the blood-brain barrier have more reported memory and “fuzzy head” problems. While patients have reported these symptoms, further research does not show that statins cause memory loss.SimvastatinSimvastatinSimvastatin has an average rating of 5.0 out of 10 from a total of 112 ratings on Drugs.com. 34% of those users who reviewed Simvastatin reported a positive effect, while 45% reported a negative effect.www.drugs.com › comments › simvastatinSimvastatin Reviews & Ratings at Drugs.com and atorvastatin are the most lipophilic while pravastatinpravastatinPravastatin belongs to a group of medicines called statins. It’s used to lower cholesterol if you’ve been diagnosed with high blood cholesterol. It’s also taken to prevent heart disease, including heart attacks and strokes.www.nhs.uk › medicines › pravastatinPravastatin: a medicine used to lower cholesterol – NHS and CrestorCrestorRelative to other statins, rosuvastatin possesses a greater number of binding interactions with HMG-CoA reductase and has a high affinity for the active site of the enzyme. Rosuvastatin is relatively hydrophilic and is selectively taken up by, and active in, hepatic cells.pubmed.ncbi.nlm.nih.gov › Rosuvastatin: a new inhibitor of HMG-coA reductase for the are the least. The statinsstatins: any of a group of drugs (such as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma.www.merriam-webster.com › dictionary › statinStatin | Definition of Statin by Merriam-Webster that cross the blood-brain barrier have more reported memory and “fuzzy head” problems. While patients have reported these symptoms, further research does not show that statins cause memory loss.

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Also, Can statins cause memory problems?

“Statins do NOT cause memory loss despite fears they could harm cognitive health,” reports the Mail Online. Statins are widely prescribed to lower cholesterol in people at risk of a heart attack or stroke. However, some people have reported problems with memory or thinking abilities (cognition) after starting statins.

Hereof, Does lipitor cause memory loss?

Neurological side effects The FDA warns on statin labels that some people have developed memory loss or confusion while taking statins. These side effects reverse once you stop taking the medication.

Does atorvastatin cause dementia?

The researchers found no evidence that using statins caused memory loss or dementia. In fact, there was some evidence that long-term statin use may protect against dementia. Scientists believe this is because certain types of dementia are caused by small blockages in blood vessels that carry blood to the brain.

Likewise, Can statins cause mental confusion?

Neurological side effects The FDA warns on statin labels that some people have developed memory loss or confusion while taking statins. These side effects reverse once you stop taking the medication.


29 Related Question Answers Found

 

What are the neurological side effects of statins?

The most common adverse effects include muscle symptoms, fatigue and cognitive problems. A smaller proportion of patients report peripheral neuropathy—burning, numbness or tingling in their extremities—poor sleep, and greater irritability and aggression.

Can statins cause personality changes?

Psychiatric adverse effects, altering mood, personality, and behavior, sometimes arise in patients receiving statins. Statin psychiatric effects can include irritability/aggression, anxiety or depressed mood, violent ideation, sleep problems including nightmares, and possibly suicide attempt and completion.

What are the side effects of atorvastatin?

– Gastrointestinal symptoms such as diarrhea.
– Cold symptoms such as a runny or stuffy nose.
– Joint pain.
– Insomnia.
– Urinary tract infection.
– Nausea.
– Loss of appetite.
– Indigestion symptoms such as stomach discomfort or pain.

What happens if you forget to take atorvastatin?

If you miss a dose of LIPITOR, take it as soon as you remember. Do not take LIPITOR if it has been more than 12 hours since you missed your last dose. Wait and take the next dose at your regular time. Do not take 2 doses of LIPITOR at the same time.

Is there a link between statins and dementia?

Use of Statin and Dementia Risk A total of 30 studies evaluated the association between statin use and all-caused dementia risk. Statin use was significantly associated with a decreased risk of dementia (RR 0.832, 95% CI 0.793–0.872, p < 0.0001).

Can statins cause neurological problems?

– Statin drugs can increase the risk of developing peripheral neuropathy, according to a study published in the May 14 issue of Neurology, the scientific journal of the American Academy of Neurology.

Which statin has the least amount of side effects?

In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications.

Can statins cause tingling?

Rare side effects of statins include: muscle weakness (myopathy) loss of sensation or tingling in the nerve endings of the hands and feet (peripheral neuropathy)

Is neuropathy a side effect of statins?

Muscle diseases are the most common side-effects of statins, which could manifest ranging from mild muscle weakness to severe rhabdomyolysis (10, 12–14). Peripheral neuropathy is a probable side-effect of these drugs.

Which statin is least likely to cause muscle pain?

Even though all statins look similar chemically, they have some minor differences that could impact how likely they are to cause muscle pain. Simvastatin is the most likely to cause muscle pain, and fluvastatin and pitavastatin are the least likely.Even though all statinsstatins: any of a group of drugs (such as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma.www.merriam-webster.com › dictionary › statinStatin | Definition of Statin by Merriam-Webster look similar chemically, they have some minor differences that could impact how likely they are to cause muscle pain. SimvastatinSimvastatinSimvastatin has an average rating of 5.0 out of 10 from a total of 112 ratings on Drugs.com. 34% of those users who reviewed Simvastatin reported a positive effect, while 45% reported a negative effect.www.drugs.com › comments › simvastatinSimvastatin Reviews & Ratings at Drugs.com is the most likely to cause muscle pain, and fluvastatinfluvastatinFluvastatin is an oral, cholesterol-lowering drug. It belongs to a class of drugs called HMG-CoA reductase inhibitors, commonly called “statins.” Other statins include lovastatin (Mevacor), atorvastatin (Lipitor), simvastatin (Zocor), and rosuvastatin (Crestor).www.medicinenet.com › fluvastatin › articlefluvastatin (Lescol, Lescol XL): Statin Drug Side Effects, Dosage and pitavastatinpitavastatinThese studies had treatment duration of up to 12 weeks. Other adverse reactions reported from clinical studies were arthralgia, headache, influenza, and nasopharyngitis. Hypersensitivity reactions including rash, pruritus, and urticaria have been reported with LIVALO.www.rxlist.com › livalo-side-effects-drug-centerSide Effects of Livalo (Pitavastatin), Warnings, Uses – RxList are the least likely.

What are the most common side effects of atorvastatin?

Commonly reported side effects of atorvastatin include: hemorrhagic stroke, arthralgia, diarrhea, and nasopharyngitis. Other side effects include: urinary tract infection, insomnia, limb pain, muscle spasm, musculoskeletal pain, myalgia, and nausea.

Can statin drugs cause nerve damage?

Muscle diseases are the most common side-effects of statins, which could manifest ranging from mild muscle weakness to severe rhabdomyolysis (10, 12–14). Peripheral neuropathy is a probable side-effect of these drugs.


Last Updated: 14 days ago – Co-authors : 8 – Users : 4

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